abstract：BACKGROUND:Invossa™ (TissueGene-C) is a cell and gene therapy for osteoarthritis. It is composed of primary human chondrocytes (hChonJ cells) and irradiated human chondrocytes modified to express TGF-β1 (hChonJb#7 cells). The hChonJ cells were isolated from a polydactyly donor, and TGF-β1 cDNA was delivered to the cell...

journal_title：BMC musculoskeletal disorders

authors： Lim CL,Lee YJ,Cho JH,Choi H,Lee B,Lee MC,Kim S

更新日期：2017-05-18 00:00:00

abstract：BACKGROUND:Studies exploring the association between physical activity, screen time and sleep and pain usually focus on a limited number of painful body sites. Nevertheless, pain at different body sites is likely to be of different nature. Therefore, this study aims to explore and compare the association between time s...

journal_title：BMC musculoskeletal disorders

authors： Silva AG,Sa-Couto P,Queirós A,Neto M,Rocha NP

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:There are varieties of self-assessment questionnaire used for the evaluation of pain, functional disability, and health related quality of life in individuals with knee osteoarthritis (OA). The present study intended to adapt and translate the oxford knee score into the Arabic and investigated its psychometr...

journal_title：BMC musculoskeletal disorders

authors： Alghadir AH,Al-Eisa ES,Anwer S

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:To systematically review and assess the efficacy and safety of hydroxychloroquine (HCQ) for treating primary Sjogren's syndrome (pSS). METHODS:Five electronic databases (Pubmed, EMBASE, Web of science, Ovid, Cochrane Library) were searched for randomized controlled trials and retrospective or prospective st...

journal_title：BMC musculoskeletal disorders

authors： Wang SQ,Zhang LW,Wei P,Hua H

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Low back pain (LBP) is an increasingly common condition worldwide with significant costs associated with its management. Identification of musculoskeletal risk factors that can be treated clinically before the development of LBP could reduce costs and improve the quality of life of individuals. Therefore the...

journal_title：BMC musculoskeletal disorders

authors： Sadler SG,Spink MJ,Ho A,De Jonge XJ,Chuter VH

更新日期：2017-05-05 00:00:00

abstract：BACKGROUND:Intermittent parathyroid hormone (PTH) can be used to treat osteoporosis of the spine and hip. However, whether it can be used to treat osteoporosis of the mandible is unclear. The purpose of this study was to explore the influence of applying intermittent PTH to ovariectomized rats on the trabecular bone mi...

journal_title：BMC musculoskeletal disorders

authors： Chen YJ,Wang SP,Cheng FC,Hsu PY,Li YF,Wu J,Huang HL,Tsai MT,Hsu JT

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually associated with three-joint complex degeneration. Schmorl's nodes (SNs) are described as vertical herniation of the disc into the vertebral body through a weakened part of the end plate that can lead to disc dege...

journal_title：BMC musculoskeletal disorders

authors： Abbas J,Slon V,Stein D,Peled N,Hershkovitz I,Hamoud K

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Avulsion fractures of the pelvic apophyses typically occur in adolescent athletes due to a sudden strong muscle contraction while growth plates are still open. The main goals of this systematic review with meta-analysis were to summarize the evidence on clinical outcome and determine the rate of return to sp...

journal_title：BMC musculoskeletal disorders

authors： Eberbach H,Hohloch L,Feucht MJ,Konstantinidis L,Südkamp NP,Zwingmann J

更新日期：2017-04-19 00:00:00

abstract：BACKGROUND:Impaired lumbo-pelvic movement in people with low back pain during bending task has been reported previously. However, the regional mobility and the pattern of the lumbo-pelvic movement were found to vary across studies. The inconsistency of the findings may partly be related to variations in the speed at wh...

journal_title：BMC musculoskeletal disorders

authors： Tsang SMH,Szeto GPY,Li LMK,Wong DCM,Yip MMP,Lee RYW

更新日期：2017-04-17 00:00:00

abstract：BACKGROUND:Teriparatide (recombinant human parathyroid hormone 1-34) is increasingly used for the treatment of severe osteoporosis because it stimulates bone formation and may potentially enhance fracture healing. The objective of this study was to investigate the effects of teriparatide versus a bisphosphonate on radi...

journal_title：BMC musculoskeletal disorders

authors： Iwata A,Kanayama M,Oha F,Hashimoto T,Iwasaki N

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:Data about minimally invasive surgery for the treatment of patients with degenerative disc disease (DDD) has been reported. However, no quantitative knowledge about the biomechanical characteristics of the spinous processes in patients with DDD after operation was reported in the literature. METHODS:Fourtee...

journal_title：BMC musculoskeletal disorders

authors： Zhang B,Huang W,Xia H,Feng X

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Danish patients with musculoskeletal disorders are commonly referred for primary care physiotherapy treatment but little is known about their general health status, pain diagnoses, clinical course and prognosis. The objectives of this study were to 1) describe the clinical course of patients with musculoskel...

journal_title：BMC musculoskeletal disorders

authors： de Vos Andersen NB,Kent P,Hjort J,Christiansen DH

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Spinal pain in children and adolescents is a common condition, usually transitory, but the picture of spinal pain still needs elucidation, mainly due to variation in measurement methods. The aim of this study was to describe the occurrence of spinal pain in 8-15 year-old Danish school children, over a 3-year...

journal_title：BMC musculoskeletal disorders

authors： Dissing KB,Hestbæk L,Hartvigsen J,Williams C,Kamper S,Boyle E,Wedderkopp N

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Total knee arthroplasty (TKA) is the most frequently performed joint replacement surgery in North America. Patient perspectives on TKA have been investigated in various ways, including finding as many as 20% of TKA patients are dissatisfied with their surgical outcomes. Understanding the patient experience w...

journal_title：BMC musculoskeletal disorders

authors： Goldsmith LJ,Suryaprakash N,Randall E,Shum J,MacDonald V,Sawatzky R,Hejazi S,Davis JC,McAllister P,Bryan S

更新日期：2017-03-24 00:00:00

abstract：BACKGROUND:The optimal method for the reduction and fixation of posterior malleolar fracture (PMF) remains inconclusive. Currently, both of the indirect and direct reduction techniques are widely used. We aimed to compare the reduction quality and clinical outcome of posterior malleolar fracture managed with the direct...

journal_title：BMC musculoskeletal disorders

authors： Shi HF,Xiong J,Chen YX,Wang JF,Qiu XS,Huang J,Gui XY,Wen SY,Wang YH

更新日期：2017-03-14 00:00:00

abstract：BACKGROUND:Upright head and neck position has been frequently applied as baseline for diagnosis of neck problems. However, the variance of the position after cervical motions has never been demonstrated. Thus, it is unclear if the baseline position varies evenly across the cervical joints. The purpose was to assess rep...

journal_title：BMC musculoskeletal disorders

authors： Wang X,Lindstroem R,Carstens NP,Graven-Nielsen T

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Ankle distraction arthroplasty is one option for the treatment of severe ankle arthritis in young patients. The outcomes and factors predicting success in distraction arthroplasty are poorly understood. METHODS:From January 2011 to May 2015, 16 patients who had undergone ankle distraction arthroplasty for a...

journal_title：BMC musculoskeletal disorders

authors： Xu Y,Zhu Y,Xu XY

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:The primary objective of this study was to assess the interobserver and intraobserver agreement on ligamentous injuries on conventional magnetic resonance imaging (MRI) in acute simple elbow dislocation. The secondary objectives were to determine the interobserver agreement on the assessment of joint congrui...

journal_title：BMC musculoskeletal disorders

authors： Schnetzke M,Schüler S,Hoffend J,Simon R,Keil H,Porschke F,Studier-Fischer S,Grützner PA,Guehring T

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting, hypophosphatemia, reduction of 1,25-dihydroxyl vitamin D, and bone calcification disorders. Tumors associated with TIO are typically phosphaturic mesenchymal tumors that are bone and soft tissue origi...

journal_title：BMC musculoskeletal disorders

authors： Arai R,Onodera T,Terkawi MA,Mitsuhashi T,Kondo E,Iwasaki N

更新日期：2017-02-13 00:00:00

abstract：BACKGROUND:Amputations in general and amputations of upper extremities, in particular, have a major impact on patients' lives. There are only a few long-term follow-up reports of patients after macro-replantation. We present our findings in contrast with the existing literature. METHODS:Sixteen patients with traumatic...

journal_title：BMC musculoskeletal disorders

authors： Mattiassich G,Rittenschober F,Dorninger L,Rois J,Mittermayr R,Ortmaier R,Ponschab M,Katzensteiner K,Larcher L

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of intermediate biologic potential. Because of its rarity and nonspecific radiological and diverse pathological findings, AFH is often clinically misdiagnosed. However, few clinical reports have described this tumor. As reported herein, we an...

journal_title：BMC musculoskeletal disorders

authors： Saito K,Kobayashi E,Yoshida A,Araki Y,Kubota D,Tanzawa Y,Kawai A,Yanagawa T,Takagishi K,Chuman H

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:Osteochondral lesions of the talus (OLTs) are amongst the most common foot and ankle disorders. Varus ankle malalignment causes stress concentration on medial side of the joint, resulting in OLTs and osteoarthritis. For large symptomatic OLTs (>10 mm), Osteochondral autograft transplantation is usually recom...

journal_title：BMC musculoskeletal disorders

authors： Li X,Zhu Y,Xu Y,Wang B,Liu J,Xu X

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Destructive spondyloarthropathy (DSA) is one of the major complications in patients undergoing long-term hemodialysis. To the best of our knowledge, an epidural abscess occurring at the level of preexisting cervical DSA has not been well described in the literature. We report a unique case of quadriplegia ca...

journal_title：BMC musculoskeletal disorders

authors： Lee JS,Ryu JH,Park JT,Kim KW

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Chronic diseases and multimorbidity are increasingly common among persons in working age. This study explores the impact of type, number and combinations of chronic diseases with focus on the role of MSKD on (1) adverse work status (i.e. work disability (WD), economic unemployment (UE) or receiving a living ...

journal_title：BMC musculoskeletal disorders

authors： van der Zee-Neuen A,Putrik P,Ramiro S,Keszei A,de Bie R,Chorus A,Boonen A

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Charcot neuropathic arthropathy (CN) is a chronic, progressive, destructive, non-infectious process that most frequently affects the bone architecture of the foot in patients with sensory neuropathy. We evaluated the outcome of protected weightbearing treatment of CN in unilaterally and bilaterally affected ...

journal_title：BMC musculoskeletal disorders

authors： Renner N,Wirth SH,Osterhoff G,Böni T,Berli M

更新日期：2016-12-29 00:00:00

abstract：BACKGROUND:Patients with lower extremity amputation frequently suffer from socket-related problems. This seriously limits prosthesis use, level of activity and health-related quality of life (HRQoL). An additional problem in patients with lower extremity amputation are asymmetries in gait kinematics possibly accounting...

journal_title：BMC musculoskeletal disorders

authors： Leijendekkers RA,Staal JB,van Hinte G,Frölke JP,van de Meent H,Atsma F,Nijhuis-van der Sanden MW,Hoogeboom TJ

更新日期：2016-11-22 00:00:00

abstract：BACKGROUND:Changes to the integrity of the acromioclavicular (AC) joint impact scapulothoracic and clavicular kinematics. AC ligaments provide anterior-posterior stability, while the coracoclavicular (CC) ligaments provide superior-inferior stability and a restraint to scapular internal rotation. The purpose of this ca...

journal_title：BMC musculoskeletal disorders

authors： Walley KC,Haghpanah B,Hingsammer A,Harlow ER,Vaziri A,DeAngelis JP,Nazarian A,Ramappa AJ

更新日期：2016-11-17 00:00:00

abstract：BACKGROUND:The use of corticosteroids (e.g., dexamethasone) as treatment for tendinopathy has recently been questioned as higher risks for ruptures have been observed clinically. In vitro studies have reported that dexamethasone exposed tendon cells, tenocytes, show reduced cell viability and collagen production. Littl...

journal_title：BMC musculoskeletal disorders

authors： Spang C,Chen J,Backman LJ

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SSc) is a rheumatologic disease with a multifactorial etiology. Genome-wide association studies imply a polygenic, complex mode of inheritance with contributions from variation at the human leukocyte antigen locus and non-coding variation at a locus on chromosome 6p21, among other modestl...

journal_title：BMC musculoskeletal disorders

authors： Cardinale CJ,Li D,Tian L,Connolly JJ,March ME,Hou C,Wang F,Snyder J,Kim CE,Chiavacci RM,Sleiman PM,Burnham JM,Hakonarson H

更新日期：2016-11-09 00:00:00

abstract：BACKGROUND:The purpose of this study was to test the hypothesis that a health and wellness coaching (HWC)-based intervention for fibromyalgia (FM) would result in sustained improvements in health and quality of life, and reductions in health care utilization. METHODS:Nine female subjects meeting American College of Rh...

journal_title：BMC musculoskeletal disorders

authors： Hackshaw KV,Plans-Pujolras M,Rodriguez-Saona LE,Moore MA,Jackson EK,Sforzo GA,Buffington CA

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Institutionalization after hip fracture is a socio-economical burden. We examined the predictive value of Instrumental Activities of Daily Living (IADL) and Mini Mental State Examination (MMSE) for institutionalization after hip fracture to identify patients at risk for institutionalization. METHODS:Fragili...

journal_title：BMC musculoskeletal disorders

authors： Hongisto MT,Nuotio M,Luukkaala T,Väistö O,Pihlajamäki HK

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:Aseptic loosening is a significant impediment to joint implant longevity. Prosthetic wear particles are postulated to play a central role in the onset and progression of periprosthetic osteolysis, leading to aseptic loosening of the prosthesis. METHODS:We investigated the inhibitory effects of a lentivirus-...

journal_title：BMC musculoskeletal disorders

authors： Qin CQ,Huang DS,Zhang C,Song B,Huang JB,Ding Y

更新日期：2016-10-18 00:00:00

abstract：BACKGROUND:Previous studies suggested that pre-operative comorbidity was a risk factor for worse outcomes after TKA. To our knowledge, studies have not examined whether postoperative changes in comorbidity impact pain and function outcomes longitudinally. Our objective was to examine if increasing comorbidity postopera...

journal_title：BMC musculoskeletal disorders

authors： Hilton ME,Gioe T,Noorbaloochi S,Singh JA

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:The 6-minute walk test (6MWT) is a commonly used metric for measuring change in mobility after knee arthroplasty, however, what is considered an improvement after surgery has not been defined. The determination of important change in an outcome assessment tool is controversial and may require more than one a...

journal_title：BMC musculoskeletal disorders

authors： Naylor JM,Mills K,Buhagiar M,Fortunato R,Wright R

更新日期：2016-09-13 00:00:00

abstract：BACKGROUND:The Goutallier Classification is a semi quantitative classification system to determine the amount of fatty degeneration in rotator cuff muscles. Although initially proposed for axial computer tomography scans it is currently applied to magnet-resonance-imaging-scans. The role for its clinical use is controv...

journal_title：BMC musculoskeletal disorders

authors： Gilbert F,Böhm D,Eden L,Schmalzl J,Meffert RH,Köstler H,Weng AM,Ziegler D

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:There are many different reasons why patients could be experiencing pain in the gluteal area. Previous studies have shown an association between radicular low back pain (LBP) and gluteal pain (GP). Studies locating the specific level responsible for gluteal pain in lumbar disc hernias have rarely been report...

journal_title：BMC musculoskeletal disorders

authors： Fang G,Zhou J,Liu Y,Sang H,Xu X,Ding Z

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:The incidence and severity of football-related injuries has been found to differ strongly between professional leagues from different countries. The aims of this study were to record the incidence, type and severity of injuries in Kosovarian football players and investigate the relationship between injury in...

journal_title：BMC musculoskeletal disorders

authors： Shalaj I,Tishukaj F,Bachl N,Tschan H,Wessner B,Csapo R

更新日期：2016-08-12 00:00:00

abstract：BACKGROUND:We examined pain levels in 2 cohorts assembled from the British Society for Rheumatology Biologics Register (BSRBR), and investigated which factors predicted Bodily Pain scores and discontinuation of TNFα-inhibitors. METHOD:Data were retrieved from BSRBR-RA databases for up to 1 year after commencing TNFα-i...

journal_title：BMC musculoskeletal disorders

authors： McWilliams DF,Walsh DA

更新日期：2016-08-12 00:00:00

abstract：BACKGROUND:This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20-40 years in a nationwide population database in Taiwan. METHODS:Subjects were selected from Taiwan's National Health Insurance Research Database for the period 2001-2008 and were followed up until the end of 201...

journal_title：BMC musculoskeletal disorders

authors： Leu TH,Chang WC,Lin JC,Lo C,Liang WM,Chang YJ,Shih DP,Wu CC,Cheng CF,Wei SJ

更新日期：2016-08-05 00:00:00

abstract：BACKGROUND:Juvenile idiopathic arthritis (JIA) refers to a number of rare chronic inflammatory diseases. Although JIA imposes a significant societal burden, limited data are available on the cost of JIA. The study's objective is to quantify the socioeconomic burden of JIA patients in the United Kingdom (UK), along with...

journal_title：BMC musculoskeletal disorders

authors： Angelis A,Kanavos P,López-Bastida J,Linertová R,Serrano-Aguilar P,BURQOL-RD Research Network.

更新日期：2016-08-02 00:00:00